Researchers stories Cure Infant HIV Patients

A woman from Mississippi U.S. toddlers add researchers hope will cure people with the HIV virus after a toddler was declared cured of the virus that attacked him since birth . Previously , researchers conducted a drug antiretroviral therapy or HAART to the toddler .

Now , virulent virus in the blood flowing toddler 's three-year -old woman had been declared missing , reported the Los Angeles Times , Friday, October 25, 2013 .

" The tests found no HIV - 1 RNA levels were detected in his blood , " said the researchers in a report the New England Journal of Medicine .

How did it come ?

Investigators strongly suspect that the three -drug cocktail that big berandil prevent the HIV virus damages the immune system 's toddler . Three cocktail that included zidovudine , lamivudine and nevirapine .

The first dose is given at 30 hours after birth . A week later , the doctor giving the drug nevirapine to the type of ritonavir - lopinavir . Continued treatment , the researchers say , is able to suppress the virus began to decline .

However , over time , the mother reportedly decided to stop doing therapy as toddlers aged 15 months , even up to 18 months old baby he had never taken antiretroviral drugs again . Unknown reason , surrender or lack of funds .

Five months later , the little girl was taken to a clinic to check the development of virus ferociously .

Surprising test results . There are no signs of the virus in blood samples . The test results were then confirmed again in the blood sample to the age of 24 , 26 , and 28 months .

At 24 months of age blood samples , had found a single copy of the viral RNA , but the ultra- sensitive test two months later failed to detect the virus copies . Negative .

" At the age of 36 months , after 18 months of HAART discontinuation of therapy , the toddler did not have detectable levels of HIV - 1 RNA , " wrote the researchers .

When these results were first announced in March , some doctors wonder and wonder , whether the toddler actually have HIV in the first time .

However , reports New England Journal of Medicine convincing evidence , that the toddler was actually infected with the virus in the womb . When blood samples were taken 30 hours after birth , blood proved that toddlers contained HIV - 1 DNA .

The doctor also denied allegations that the experts that the toddler had a rare mutation that makes it resistant to the virus .

"He does not have a rare mutation . Growth and development have been normal , " said the doctor .

other therapies

Healing toddler was not the first time . Previously , an HIV patient , Timothy Ray Brown was declared cured after treatment , the bone marrow transplant .

This option was given Brown suffered acute myeloid leukemia . Doctors perform rare genetic mutation by blocking the HIV virus is in the cell .

Unfortunately, bone marrow gene therapy is very risky . First, it can lead to death in patients suffering from cancer . In addition very few find a suitable bone marrow donor to a patient's immune system .

To that end , researchers more merekomedasikan antiretroviral drug therapy as in the case of the Mississippi toddler origin .

This toddler successful case led researchers support the idea immediately provide antiretroviral therapy in infants born to prevent virus attacks the immune system .

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